AptamiR Therapeutics, Inc.

[Available On-Demand]
• Structure: AptamiR is an American modular Biotechnology Company developing pre-clinical drug candidates
• Mission: Treat fat accumulation, inflammation and fibrosis to cure related cardiometabolic disorders (obesity, dyslipidemia, diabetes and metabolic dysfunction-associated fatty liver disease (MAFLD)) without altering brain functions while improving quality of life of patients
• Strategy: Transform fat-storing cells (white adipocytes) into fat-burning cells (“browning effect”) to increase lipid oxidation, mitochondrial activity and energy expenditure
• Accomplishment to date: Proofs of efficacy for our first generation of oligonucleotides therapeutics (ONTs) targeting miRNAs achieved in human adipocytes in culture and in animal models
• Goal for the next 24 months: Complete the pre-IND and IND phases for the second generation of miR-22-3p Antagomirs to treat obesity, diabetes and fatty liver disease
• Gap to achieve this goal: Secure first tranche ($5M) of Series B financing
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United States
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miR-22 antagomir
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Founder & President
AptamiR Therapeutics, Inc.