Charcot-Marie-Tooth Association

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The CMTA STAR (Strategy to Accelerate Research) Consortium was launched as a means to facilitate collaboration and accelerate therapy development for scientists, clinical researchers and pharmaceutical companies working on Charcot-Marie-Tooth neuropathy disorders. CMT disorders taken together have a disease frequency of 1:2500, are of known genetic causation, and lack available therapies, making them attractive candidates for therapy development.

The CMTA has assembled preclinical “toolboxes” for different CMT disorders, allowing proof-of-principle testing of the role of a therapeutic target in the disease process, and of the ability of a therapy directed to this target to arrest or even reverse the pathology. Alliances are conducted via a broad CMT expert and pharmaceutical testing network that includes services for study planning and project execution, therapy evaluation via a network of leading specialty CRO’s, and straightforward agreements for protecting and sharing data.
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HumanFirst Therapeutics LLC