Actinogen Medical

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Actinogen Medical (ASX:ACW): an ASX-listed biotechnology company developing novel therapies for cognitive impairment associated with significant neurological and metabolic diseases, including Alzheimer’s disease (AD).

Actinogen Medical’s lead drug, Xanamem, has been specifically designed to reduce production of excess cortisol in the brain via antagonism of neuronally expressed 11β-HSD1. Chronically raised cortisol is a key risk factor for AD, and the association between raised cortisol and cognitive decline has been well documented in the scientific literature. Drugs that reduce cortisol in the brain offer a promising new approach to slowing, or even preventing, the cognitive decline associated with AD and a range of other neurological disorders.

Actinogen is refining a clinical development strategy aimed at initiating multiple phase II studies; including in AD (patients with mild cognitive impairment), cognitive impairment in schizophrenia, diabetes, and other indications.
Australian Stock Exchange (ASX)
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Family of brain-penetrant 11B-HSD1 inhibitors with Xanamem as lead compound
CEO & Managing Director
Actinogen Medical