Salspera has emerged as a leader in the field of microbial immunotherapy. The company has created a platform of orally administered tumor microbiome immunotherapies, genetically engineered to eliminate pathogenicity and express various cytokines and cytotoxic proteins within the tumor microenvironment. One of these therapies is Saltikva, an orally administered, unique, non-toxic cancer therapeutic that acts synergistically with conventional chemotherapy. Saltikva is an attenuated Salmonella Typhimurium containing the gene for human Interleukin-2. Recently, Saltikva was released on a compassionate basis to a patient with metastatic pancreatic cancer. With a median life expectancy of just 11 months, this patient is now in month 30 post-diagnosis and is feeling extremely well with complete resolution of her pulmonary metastases and significant diminution of her liver metastases and primary pancreatic cancer. A Phase II clinical study of Saltikva in metastatic pancreatic cancer is currently ongoing (NCT04589234).
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