Minerva Biotechnologies

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Minerva Biotechnologies is a clinical-stage company with a near-term pipeline protected by an IP fortress. huMNC2-CAR44 T cells are in a 1st-in-human Phase I/II trial for metastatic breast cancers (NCT04020575) at the Fred Hutchinson/Bezos Immunotherapy Clinic; trial is now expanding to City of Hope and the Barbara Ann Karmanos Cancer Institute. Efficacy has been measured in nearly every patient, even at the lowest dosage. To date, no adverse events attributed to the therapy. 2021 IND submission planned for 1XX version of this CAR-T for increased persistence. Target molecule is expressed on over 75% of all solid tumors. Pipeline includes antibody against the onco-embryonic growth factor and a small molecule. Both show robust inhibition/prevention of metastasis in animals.
Company Type:
Privately Funded Company
Company Website:
Company HQ State:
Massachusetts
Company HQ Country:
United States
Year Founded:
1999
Main Therapeutic Focus:
Lead Product in Development:
1st-in-human CAR T Phase I/II trial at Fred Hutchinson NCT04020575
Development Phase of Primary Product:
Number Of Unlicensed Products (For Which You Are Seeking Partners):
1) huMNC2-CAR44 T; 2) huMNC2-CAR28-1XX T; 3) Anti-onco-embryonic growth factor MN4A3
Speaker
photo
Chief Executive Officer
Minerva Biotechnologies Corporation