Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA.
By leveraging its unique ability to manufacture DNA at scale, Twist Biopharma, a division of Twist Bioscience, can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. This Library of Libraries gives Twist Biopharma partners an integral and unbiased resource for antibody discovery and optimization. This precise and rational approach to library fabrication combined with sophisticated bioinformatics and software expertise expedites antibody discovery by decreasing risk, increasing speed, and lowering the failure rate for antibody development.
In addition, our team is focused on discovery of antibody drug candidates with a high affinity and a potent effect against those targets of well-documented therapeutic interest yet “hard to drug”, such as G protein-coupled receptors (“GPCRs”). Some of these assets have advanced to preclinical development and are available for licensing.