Dan Close obtained his doctorate from The University of Tennessee, where he developed a novel pre-clinical biomedical imaging technology for autonomous bioluminescent production in human and animal cells. Following development, this technology was commercialized by 490 BioTech in 2011. After graduation, Dr. Close worked as a Postdoctoral Research Associate in the Joint Institute for Biological Sciences at Oak Ridge National Laboratory. In 2012 Dr. Close was selected as a Eugene P. Wigner Fellow by the Department of Energy. Leveraging his synthetic genetic pathway design experience, Dr. Close’s research centered on the development of hydrocarbon biofuels using industrially relevant organisms. Following completion of his fellowship, Dr. Close continued his work as a Research Staff Scientist before leaving in 2018 to become the chief scientific officer of 490 BioTech, the company founded on the autobioluminescent technology he developed during his graduate work.