For over twelve years, Aruna manufactured and provided neural stem cells to the world’s leading research organizations with unrivaled uniformity and scale. Today, Aruna Bio is advancing a new class of cell-free biologics, neural exosomes, for the treatment of central nervous system (CNS) injury and degenerative disorders. As experts in the design and scaling of neural-derived exosomes, Aruna Bio is rapidly moving toward clinical development of a new class of cell-free exosome biologics and exosome-mediated drug delivery systems. To date, our exosomes have demonstrated the ability to be safely administered intravenously in multiple doses with no adverse side effects, cross the blood-brain barrier non-invasively to reach the site of injury, reduce inflammation and enhance neural function, and improve motor function and behavioral outcomes in large and small preclinical models.
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