Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan as well as interventions for serious age-related diseases. We have assembled an outstanding team of scientists with diverse backgrounds and expertise in biology, aging, medicine, genetics, machine learning and informatics, and drug development. In addition to Calico’s internal efforts, executing on this mission will require collaborations and partnerships with the leading academic institutions and biotechnology companies that share our vision. Therapeutic areas of key interest for Calico include oncology, neurodegeneration, chronic inflammation and metabolic dysfunction because the incidence of these conditions rises sharply in advanced age and is associated with great morbidity. We are most interested in external opportunities at the research and early development stage within these areas of focus.