Engine Biosciences is a venture-backed biotechnology company deciphering biological complexity to enable transformative precision products. Engine’s proprietary NetMAPPR(TM) platform integrates network-based computation and machine learning, combinatorial CRISPR screens, and drug discovery to explore the entire genetic interaction space and unveil novel biology-led, human data-driven product opportunities across therapeutics areas. Lead product categories in the pipeline include precision therapeutics for key targets in genetically defined contexts and combination therapies. Engine is applying the platform internally and with partners across a range of disease indications, with several product opportunities validated and progressing towards the clinic. Based in Singapore and San Francisco Bay Area, Engine’s founders and leadership team include pioneering professors at MIT and Harvard, successful company builders, and drug discovery experts with multiple FDA-approved therapeutics.
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Cancer - small molecule targeted therapy - Novel Target, Lead Identification stage
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