Vaccines for COVID-19 were developed, produced and made available in developed countries in less than one year. This accomplishment was unforeseen just 3 years ago. The potential for platform technologies like mRNA to shorten the development and manufacturing timing of vaccines could fundamentally change the way the world prepares for and responds to potential pandemics. In June 2021 G7 leaders put forth the concept of developing, manufacturing and distributing vaccines against a pathogen of pandemic potential in 100 days. This concept was further explored as part of President Biden’s American Pandemic Preparedness Plan. The speakers on this panel will discuss the power of developing prototype vaccines against pathogens with pandemic potential, creating global clinical trial networks and protocols to speed research, and scaling global manufacturing to help ensure rapid and equitable access. Panelists will offer ideas and policies that can leverage new technologies and partnerships with industry to respond even more rapidly to the next epidemic or global pandemic.