Moderna announced promising results from the Phase 3 clinical trial of its next-generation COVID-19 vaccine—another step forward in addressing emerging variants and ensuring ongoing protection.
The data: Moderna’s new mRNA-1283 vaccine elicited higher immunity against Omicron BA.4/BA.5 and original SARS-CoV-2 strains than the company’s currently approved mRNA-1273.222 vaccine. The benefit was most acute in the high-risk 65-plus age group.
Why it matters: The Food and Drug Administration (FDA) recommended that COVID-19 vaccines be updated to address coronavirus mutations and be given annually like a flu shot.
The next generation: Moderna said it can combine the new COVID vaccine with a flu vaccine, encouraging uptake by providing a single, annual shot. Pfizer indicated similar plans. Moderna said the updated vaccine also has a longer shelf life and is easier to store, aiding distribution.
More innovation: Future COVID-19 protection could include multivalent vaccines targeting a range of virus strains, use of nanoparticles or viral vectors to enhance stability and effectiveness, and universal vaccines offering broad protection against diverse immunoviruses, Bio.News reports.
More benefits: Research released earlier this month found that people vaccinated against COVID-19 had a 45%-81% reduction in risk of “thromboembolic and cardiac events” compared to the unvaccinated—apparently because the vaccine reduced risk and severity of COVID-19 infection.
The bottom line: COVID-19 vaccines helped us control the pandemic and updated vaccines continue to provide the best defense.
More Health News:
Wall Street Journal: The Supreme Court and Mifepristone
"If courts start second-guessing FDA decisions, it will slow the development of life-saving treatments"
Fierce Biotech: Nanoscope eyes market after gene therapy restores vision for patients with retinal disease
“Nanoscope Therapeutics is back with more data assessing its gene therapy that uses light-sensitive molecules to treat retinal disease. With data demonstrating vision improvement in hand, the biotech is now planning to submit the therapy for FDA approval later this year.”