I am BIO Podcast

Powerful stories of biotech breakthroughs, the people they help, and the global problems they solve.

Featured Episodes & More
Is CRISPR the New Sickle Cell Savior?
Is CRISPR the New Sickle Cell Savior?

A 2023 biotech breakthrough: CRISPR gene-editing therapy offers new hope for 100,000 Americans with sickle cell. Hear from CASGEVY's creators and patient advocates in this episode.

Biotech is Climate Tech
Biotech is Climate Tech

Biotech tackles climate change with innovations, from carbon-neutral facilities to reducing emissions. At COP28, BIO highlighted that biotech is key to climate tech.

Editing Cells Within the Body—a New CRISPR Frontier
Editing Cells Within the Body—a New CRISPR Frontier

CRISPR, biotech's rising star, reached a 2023 milestone with FDA approval for a sickle cell treatment. This episode explores the future of in-body gene editing with two pioneering companies.

Listener takeover: Your Biotech Questions Answered
Listener takeover: Your Biotech Questions Answered

In this episode, experts answer your questions on GMO safety, personalized medicine, feeding the world by 2050, and what attracts investors to start-ups.

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How Love Combined with Science Leads to Hope for Rare Disease
Episode 89  •  Oct 22, 2024  •  27 min

There are over 7000 rare diseases identified in the U.S. alone. Many of these diseases affect children, leaving families desperate for answers. In this episode, we talk with one of those families and the biotech company offering them new hope. We also talk with an expert on policy that has jump-started R&D for rare diseases.

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How Will We Secure our Food Future?
Episode 88  •  Oct 8, 2024  •  26 min

As the global population approaches 10 billion by 2050, the challenge of providing safe, nutritious food is growing more urgent. Climate change is further straining food systems, impacting water availability, crop yields, and livestock health. In this episode, two experts discuss innovative biotech solutions aimed at addressing these pressing issues, offering hope for a sustainable path forward in feeding the world.

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Biotechnology is a National Security Asset
Episode 87  •  Sep 24, 2024  •  27 min

Since Watson and Crick discovered DNA's double helix structure in 1953, the US has been a leader in biotechnology innovation. American excellence in this field has greatly benefited people around the world. In this episode, we talk about why this leadership position may be threatened and why that matters to our national security.

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A Doctor Fights to Save His Own Life: The David Fajgenbaum Story.
Episode 86  •  Sep 10, 2024  •  21 min

David Fajgenbaum was in his third year of medical school when he was diagnosed with a rare and life-threatening disease that began shutting down his organs, bringing him perilously close to death. Although he survived the initial episode, he faced four additional relapses, each pushing him to the brink of death. In this episode, we speak with David about his relentless journey to discover the treatment that ultimately put his disease into remission. We also explore how his personal battle inspired the creation of a groundbreaking approach to help others suffering from rare diseases.

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Listener takeover: Your Biotech Questions Answered
Episode 85  •  May 7, 2024  •  21 min

YOU asked, and we answered. In this episode, we had our experts on standby to answer questions from you, our listeners. We discuss topics ranging from the safety of genetically modified foods (GMOs), to the new era of personalized medicine, feeding the world by 2050, and even what makes start-up companies attractive to investors.

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Editing Cells Within the Body—a New CRISPR Frontier
Episode 84  •  Apr 23, 2024  •  21 min

With its potential to expand the horizons of what’s possible for patients, CRISPR is the new darling of biotech. Reaching an important milestone in 2023 with the FDA approval of a sickle cell treatment using CRISPR, the technology is poised to break new barriers for treating patients in the near future. In this episode we talk with two companies working together on the next generation of CRISPR: editing cells within the body.  We discuss the progress and the challenge in making this breakthrough a reality.

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Biotech is Climate Tech
Episode 83  •  Apr 9, 2024  •  21 min

Biotech companies are addressing climate change through innovation—from carbon neutral facilities to agricultural innovations to reduce greenhouse gas emissions. BIO was on the ground at the COP28 UN Climate Change Conference in Dubai to deliver the message that biotech is climate tech. 

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Biotech for our Pets
Episode 82  •  Mar 26, 2024  •  28 min

More than half of U.S. households include pets, but there has been a lack of medical treatments developed specifically for small animals. Biotech companies are working to change that with new treatment options that both borrow from and, potentially, advance human health discoveries.

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What We Know About the Microbiome
Episode 81  •  Mar 12, 2024  •  27 min

The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits.

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Is CRISPR the New Sickle Cell Savior?
Episode 80  •  Feb 27, 2024  •  25 min

2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. 

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