The pandemic forced support ecosystems for emerging biotechs to adapt their processes to continue despite social distancing and travel restrictions. Now, macroeconomic influences, rising inflation and climate crisis are new challenges that early stage companies face as they seek to raise capital, recruit talent and grow. This session explores lessons learned by leading support ecosystems around the world and how companies should be planning in order to improve innovation productivity. How have cross border ecosystems managed differences in travel restrictions, the ability to relocate talent, and new paradigms for funding R&D? And what are new models of acceleration and incubation we are seeing beyond incubators in both emerging and established ecosystems?